Chamber music has always been an important aspect of Wehr's career. The Sartory Trio, with violinist Charles Stegeman and cellist Jennifer Langham, was the resident chamber ensemble at Duquesne University from 1991-94 and toured cross-country for Community Concerts. Important engagements included London' s Wigmore Hall, Tannery Pond Festival in New Lebanon, New York, St. Bart' s Festival in the French West Indies, Princeton University, South Shore Music Festival in Southport, Connecticut and the International Concert Series in Red Bank, New Jersey.
Wehr has collaborated with the Moscow, Chilingirian and Quapaw String Quartets; pianists Cynthia Raim, Natasha Snitkovsky, and Helene Wickett; violinists Martin Agee, Elizabeth Baker, Nancy Bean, Viviane Bertolami, Andres Cardenes, Laura Frautschi, Jennifer Garner, Kevin He, Galina Heifetz, Julian Hallmark, Jaroslaw Lis, Janna Lower, Edith Markman, Michael Markman, Giora Schmidt, Stephen Shepard, Susan Shumway, Rachel Stegeman, Kyoko Takezawa, and Linda Wang; violists Frank Brieff, Paul Coletti, Marylene Gingras-Roy, Randolph Kelly, Linda Kirkwood, Vincent Lionti, Donald McInnes, Seth Mausner, Roger Myers, Matthew Rombaum, Nanci Severance, Sally Shumway, Clara Takarabe, and Richard Young; cellists Zuill Bailey, David Bakamjian, Colin Carr, Kim Cookand, Samuel Cristler, Kate Dillingham, Steven Elisha, David Goldblatt, Sadao Harada, James Kirkwood, Rafael Leon, Anne Martindale Williams, Emile Miland, Clancy Newman, David Premo, Misha Quint, Steven Shumway, Mariusz Skula, Mark Tanner, Steven Thomas and John Walz; double bassist Jeffrey Turner; flutists Julius Baker, Kelly Kazik, Rebecca Keen, Barry McVinneyand, and Wendy Rolfe; oboist Robin Driscoll, Doris Goltzer, Alex Klein, and Peter Stempe; clarinetists Igor Begelman and Todd Palmer; bassoonists Leonard Hindell and Frank Morelli; hornists William Caballero, James Thatcher, David Wakefield and Jessica Wiskus; organist Andrew Shenton and baritone David Malis; bass-baritone Guenko Guechev.
Wehr won the Chamber Music Prize at the 1986 Gina Bachauer International Piano Competition in Salt Lake City.
Music of composers from the United States has figured importantly in Wehr's career. His first recording, released worldwide by Chandos in 1988, was "20th-Century American Piano Music" with music by Samuel Barber, Aaron Copland, John Corigliano, Vincent Persichetti and John Pozdro.
Commissions and premieres by Joe Utterback, Victoria Burkhard, Francis McBeth, Sarah Dawson, David Cutler, Curt Cacioppo, David Stock and Jay Riese have complemented performances of music by Samuel Adler, Paul Creston, Lukas Foss, George Gershwin, Charles Tomlinson Griffes, Alan Hovhannes, Charles Ives, Scott Joplin, David Korevaar, Lowell Liebermann, Edward MacDowell, George Perle and Richard Toensing.